I use this setup for watching youtube, music and a few video games. Its way overbuilt and Im ok with that.
The vivo quad lcd stand was only rated for up to 4- 27" monitors and I managed to squeeze a 40" TV up top. still stable.
The BOSE Acoustimass speakers are run off the receiver that is hooked up to the GPU with HDMI, the TV is then ran from the receiver.